Saturday, November 4, 2021
| Final | |
| Delaware State (4-5, 1-2) | 14 |
| Morgan State (1-8, 1-4) | 20 |
| ESPN2 | |
Saturday November 6, 2021
| Final 2 OT | |
| Arizona Christian (6-3, 5-3) | 40 |
| Langston (7-2, 6-2) | 37 |
| Final | |
| SAGU (7-3, 5-3) | 63 |
| Texas College (0-10, 0-8) | 0 |
| Final | |
| 7Alcorn State (5-4, 4-2) | 31 |
| Bethune-Cookman (1-8, 1-5) | 35 |
| Final | |
| Miss Valley State (2-7, 1-5) | 14 |
| Alabama A&M (5-3, 3-3) | 42 |
| Final | |
| Lincoln (MO) (0-9, 0-9) | 21 |
| Emporia State (6-4, 6-4) | 56 |
| Final | |
| Texas Southern (2-6, 2-4) | 21 |
| 1Jackson State (8-1, 6-0) | 41 |
| Final | |
| Tuskegee (3-7, 2-4) | 23 |
| Miles (6-4, 4-2) | 52 |
| Final | |
| Elizabeth City State (3-7, 3-4) | 6 |
| 4Bowie State (9-1, 7-0) | 79 |
| Final | |
| NC A&T (4-5, 3-3) | 21 |
| Charleston Southern (3-5, 2-4) | 18 |
| Final | |
| Lincoln (PA) (1-9, 1-6) | 12 |
| Chowan (7-3, 4-3) | 28 |
| Final OT | |
| Gardner-Webb (3-6, 1-4) | 21 |
| Hampton (4-5, 2-3) | 27 |
| Final | |
| Livingstone (2-8, 2-5) | 17 |
| Johnson C. Smith (1-8, 1-6) | 3 |
| Commemorative Classic, Charlotte, NC | |
| Final | |
| Central State (1-9, 0-6) | 0 |
| Kentucky State (6-4, 4-2) | 63 |
| Final | |
| Shaw (6-4, 5-2) | 17 |
| Saint Augustine's (1-7, 1-6) | 21 |
| Raleigh Classic, Raleigh, NC | |
| Final | |
| Webber international (1-8, 0-5) | 31 |
| Florida Memorial (2-8, 1-4) | 34 |
| Final | |
| Grambling State (3-6, 2-4) | 26 |
| Arkansas-Pine Bluff (2-7, 1-5) | 33 |
| Final | |
| Alabama State (3-5, 2-4) | 20 |
| 2Prairie View A&M (7-1, 6-0) | 24 |
| Final | |
| 8Tennessee State (5-4, 3-2) | 20 |
| UT Martin (8-1, 4-0) | 41 |
| Final | |
| Fort Valley State (5-5, 3-3) | 0 |
| 6Albany State (9-1, 6-0) | 57 |
| Fountain City Classic, Columbus, GA | |
| Final | |
| Lane (6-4, 3-3) | 30 |
| Benedict (5-5, 2-4) | 34 |
| Final | |
| Morehouse (4-6, 4-2) | 35 |
| Clark Atlanta (2-8, 0-6) | 26 |
| Final | |
| Winston-Salem State (3-6, 3-4) | 3 |
| 9Fayetteville State ( 8-1, 7-0) | 10 |
| Final 2OT | |
| 5Norfolk State (6-3, 2-1) | 36 |
| NC Central (4-5, 2-1) | 38 |
| Final | |
| Howard (2-7, 1-3) | 12 |
| SC State (5-4, 4-0) | 15 |
| Final | |
| Virginia State (3-6, 3-4) | 13 |
| Virginia Union (6-4, 5-2) | 20 |
| Final | |
| West Virginia State (6-4, 6-3) | 33 |
| West Liberty (4-5, 4-6) | 28 |
| Final | |
| Edward Waters (3-7) | 0 |
| Savannah State (8-2) | 24 |
| Final | |
| 3Florida A&M (7-2, 5-1) | 29 |
| 10Southern (4-5, 3-3) | 17 |