Saturday, October 22, 2022
| Final | |
| Campbell (4-3) | 14 |
| 1 Jackson State (7-0) | 22 |
| Final | |
| Bethune-Cookman (2-5) 2-2) | 45 |
| Miss Valley State (0-8) (0-5) | 35 |
| Final | |
| VA-Lynchburg (0-7) | 7 |
| 6 Southern (5-2) | 51 |
| Final | |
| Prairie View A&M (4-3) | 54 |
| Lamar (0-7) | 21 |
| Final | |
| Texas Southern (3-4) (3-2) | 34 |
| 8 Alcorn State (3-4) (2-3) | 27 |
| Final | |
| 4 NC Central (5-2) (1-1) | 24 |
| SC State (3-4) (1-0) | 26 |
| Final | |
| Delaware State (4-3) (1-1) | 17 |
| Howard (2-5) (1-0) | 35 |
| Final | |
| Morgan State (2-5) | 7 |
| Delaware (6-1) | 38 |
| Final | |
| NC A&T (4-3) (2-0) | 38 |
| Robert Morris (0-7) (0-3) | 14 |
| Final | |
| Richmond (5-2) (3-1) | 41 |
| 10 Hampton (4-3) (1-3) | 10 |
| Final | |
| Eastern Illinois (2-5) (1-1) | 14 |
| Tennessee State (4-4) (3-0) | 37 |
| Final | |
| Bluefield State (4-3) | 14 |
| Allen (1-6) | 50 |
| Final | |
| Chowan (5-3) (5-1) | 21 |
| Bowie State (4-4) (3-3) | 15 |
| Final | |
| Edward Waters (2-6) (2-3) | 45 |
| Central State (2-6) (1-4) | 13 |
| Final | |
| Virginia State (5-3) (4-2) | 34 |
| Elizabeth City State (2-6) (2-4) | 12 |
| Final | |
| Fayetteville State (6-2) (5-1) | 21 |
| Johnson C. Smith (2-5) (2-4) | 13 |
| Final | |
| Winston-Salem State (2-5) (1-4) | 41 |
| Saint Augustine's (1-7) (1-5) | 14 |
| Final | |
| Livingstone (2-6) (1-5) | 14 |
| Shaw (3-5) (3-3) | 28 |
| Final | |
| Concord (6-2) (5-2) | 38 |
| West Virginia State (5-3) (4-3) | 58 |
| Final | |
| Florida Memorial (2-5) (0-2) | 14 |
| Webber International (4-2) (2-1) | 31 |
| Final | |
| Arizona Christian (5-2) (4-2) | 81 |
| Texas College (1-6) (1-5) | 19 |
| Final | |
| 9 Fort Valley State (7-1) (4-1) | 41 |
| Clark Atlanta (3-4) (2-3) | 21 |
| Final | |
| 2 Virginia Union (8-0) (6-0) | 45 |
| Lincoln(PA) (2-5) (1-4) | 20 |
| Final | |
| Tuskegee (6-2) (5-0) | 35 |
| Lane (4-4) (3-2) | 31 |
| Final | |
| Ottawa (5-2) (5-2) | 38 |
| Langston (6-1) (5-1) | 44 |
| Final | |
| Nebraska Kearney (6-2) (6-2) | 66 |
| Lincoln(MO) (0-8) (0-8) | 17 |
| Final | |
| Kentucky State (4-4) (4-1) | 35 |
| Miles (1-7) (1-4) | 7 |
| Final | |
| 5 Benedict (8-0) (5-0) | 35 |
| Morehouse (0-8) (0-5) | 0 |
| Final | |
| 7 Albany State 6-2) (4-1) | 31 |
| Savannah State (3-5) (2-4) | 20 |