Thursday, September 2, 2021
| Final | |
| Washburn (1-0, 1-0) | 76 |
| Lincoln (Mo.) (0-1, 0-1) | 12 |
| Final | |
| Albany State (1-0) | 24 |
| Mississippi College (0-1) | 0 |
| Final | |
| Shaw (0-1) | 7 |
| Wingate (1-0) | 30 |
| Final | |
| Miss Valley State (0-1) | 0 |
| Murray State (1-0) | 35 |
| Final | |
| Texas College (0-1) | 0 |
| West Texas A&M (1-0) | 73 |
| Final | |
| Chowan (1-0) | 30 |
| Mars Hill (0-1) | 24 |
Saturday, September 4, 2021
| Final | |
| Tusculum (1-0) | 58 |
| Saint Augustine's (0-1) | 14 |
| Final | |
| West Virginia State (0-1) | 17 |
| Shippensburg (1-0) | 25 |
| Final | |
| 2 NC A&T (0-1) | 18 |
| Furman (1-0) | 29 |
| Final | |
| Howard (0-1) | 14 |
| Richmond (1-0) | 38 |
| Final | |
| Langston (1-0, 1-0) | 10 |
| OK Panhandle State (0-1, 0-1) | 7 |
| Final | |
| 8 Bowie State (0-1) | 24 |
| Delaware State (1-0) | 32 |
| Final | |
| Fayetteville State (1-0) | 47 |
| Elizabeth City State (0-1) | 6 |
| Down East Viking Classic, Rocky Mount, NC | |
| Final | |
| Towson (1-0) | 31 |
| Morgan State (0-1) | 0 |
| Final OT | |
| Miles (0-1) | 13 |
| Alabama State (1-0) | 14 |
| Labor Day Classic, Montgomery, AL | |
| Final | |
| 6 SC State (0-1) | 41 |
| 1 Alabama A&M (1-0) | 42 |
| Louis Crews Classic, Huntsville, AL | |
| Final | |
| Lane (0-0) | 16 |
| 4 Arkansas-Pine Bluff (0-0) | 34 |
| Final | |
| 5 Southern (0-1) | 3 |
| Troy (1-0) | 55 |
| Final | |
| Morehouse (0-1) | 7 |
| West Alabama (1-0) | 48 |
| Final | |
| Allen (0-1) | 12 |
| Benedict (1-0) | 45 |
| Final | |
| Lawrence Tech (1-0) | 21 |
| Bluefield State (0-1) | 14 |
| Final | |
| Virginia Union (0-1) | 28 |
| Hampton (1-0) | 42 |
| Final | |
| Lock Haven (1-0) | 20 |
| Lincoln (Pa) (0-1) | 0 |
| Final | |
| Clark Atlanta (1-0) | 13 |
| Livingstone (0-1) | 10 |
| Final | |
| Lenoir-Rhyne (1-0) | 48 |
| Virginia State (0-1) | 7 |
| Final | |
| 10 Prairie View A&M (1-0, 1-0) | 40 |
| Texas Southern (0-1, 0-1) | 17 |
| Labor Day Classic, Houston, TX | |
| Final | |
| Norfolk (0-1) | 10 |
| Toledo (1-0) | 49 |
| Final | |
| Savannah State (0-1) | 7 |
| Valdosta State (1-0) | 53 |
| Final | |
| Bethune-Cookman (0-1) | 28 |
| UTEP (1-0) | 38 |
Sunday, September 5, 2021
| Final | |
| 7 Jackson State (1-0, 1-0) | 7 |
| 3 Florida A&M (0-1, 0-1) | 6 |
| TV:ESPN2 | |
Orange Blossom Classic, Miami Gardens, FL
| Final | |
| Tennessee State (0-1) | 10 |
| Grambling State (1-0) | 16 |
| Black College Hall of Fame Classic, Canton, OH | |
| Final | |
| Tuskegee (0-1) | 0 |
| Fort Valley State (1-0) | 30 |
| TV:ESPNU | |
Red Tails Classic, Montgomery, AL