Thursday, September 23, 2021
| Final | |
| 9Alcorn State (2-2, 1-0) | 39 |
| 3Arkansas-Pine-Bluff (1-2, 0-1) | 38 |
| ESPNU | |
Saturday, September 25, 2021
| Final | |
| Howard (0-4) | 16 |
| Robert Morris (1-1) | 22 |
| Final | |
| Virgina Union (2-2, 1-0) | 43 |
| Johnson C. Smith (0-3, 0-1) | 7 |
| Final | |
| Shaw (2-2, 1-0) | 41 |
| Lincoln (PA) (0-4, 0-1) | 6 |
| Final | |
| Chowan (4-0, 1-0) | 59 |
| Saint Augustine's (0-2, 0-1) | 12 |
| Final | |
| Elizabeth City State (1-3, 1-0) | 19 |
| Winston-Salem State (0-3, 0-1) | 14 |
| Final | |
| West Virginia State (1-3, 1-2) | 14 |
| Notre Dame (OH) (4-0, 3-0) | 38 |
| Final | |
| Norfolk State (2-2) | 28 |
| Saint Francis (PA) (1-3) | 16 |
| Final | |
| Delta State (2-2) | 17 |
| 2Jackson State (3-1) | 24 |
| Final-OT | |
| Northeastern State (2-2, 2-2) | 49 |
| Lincoln (MO) (0-3, 0-3) | 48 |
| Final | |
| Tennessee State (1-2, 0-0) | 14 |
| Southeast Missouri (0-3, 0-0) | 47 |
| Final | |
| Merrimack (3-1) | 47 |
| Delaware State (1-3) | 10 |
| Final | |
| Florida Memorial (0-5, 0-2) | 7 |
| Cumberland (1-2, 1-0) | 19 |
| Final | |
| Benedict (2-2, 0-2) | 28 |
| Kentucky State (2-2, 2-0) | 34 |
| Circle City Classic, Indianapolis, IN | |
| Final | |
| Tuskegee (1-3) | 35 |
| 1Alabama A&M (3-0) | 45 |
| Gulf Coast Classic, Mobile, AL | |
| Final | |
| 7Prairie View A&M (3-1, 2-0) | 24 |
| Grambling State (1-3, 0-1) | 10 |
| State Fair Classic, Dallas, TX | |
| Final | |
| Bowie State (3-1, 1-0) | 49 |
| Livingstone (0-4, 0-1) | 0 |
| Final | |
| Bethune-Cookman (0-4, 0-2) | 24 |
| Alabama State (2-1, 1-0) | 38 |
| Final | |
| Texas Southern (0-3) | 34 |
| Rice (1-3) | 48 |
| Final | |
| Central State (1-3, 0-2) | 4 |
| MIles (2-2, 1-0) | 55 |
| Final | |
| Fort Valley State (2-2) | 56 |
| Allen (2-2) | 20 |
| Final | |
| Lane (3-1) | 45 |
| Edward Waters (1-3) | 35 |
| Final | |
| 5NC Central (2-2) | 14 |
| 4NC A&T (1-2) | 37 |
| Final | |
| Morehouse (0-4, 0-1) | 10 |
| Savannah State (3-1, 2-0) | 29 |
| Final | |
| Clark Atlanta (1-3, 0-1) | 0 |
| Albany State (3-1, 1-0) | 49 |
| Final | |
| Virginia State (0-3, 0-1) | 14 |
| Fayetteville State (2-1, 1-0) | 28 |
| Final | |
| Arkansas Baptist (5-2) | 85 |
| Langston (4-0) | 6 |
Sunday, September 25, 2021
| Final | |
| Miss Valley state (0-3,0-1) | 25 |
| 8Southern (2-2, 1-0) | 38 |